KMID : 0388120140230030164
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Journal of Korean Society for the Study of Obesity 2014 Volume.23 No. 3 p.164 ~ p.169
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Comparison of Changes in Body Weight and Serum Lipid Profile after Roux-en-Y Gastric Bypass between Non-obese Patients and Obese Patients
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Park Jung-Hwan
Hong Sang-Mo Lee Chang-Beom Ahn You-Hern Kim Dong-Sun
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Abstract
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Background: This study was aimed to investigate the effects of bariatric surgery in non-obese patients through the comparison of the changes in body weight (BW) and serum lipid profile between non-obese and obese patients after Roux-en-Y gastric bypass.
Methods: In this study, 116 patients who received laparoscopic Roux-en-Y gastric bypass due to early gastric cancer were included. Patients were divided into two groups, non-obese group (N=76), defined as body mass index <25 kg/m2, and obese group (N=40), body mass index ¡Ã25 kg/m2. BW and serum lipid profile before surgery and at 3, 6, 9, and 12 months after surgery were examined.
Results In all groups, BW and triglyceride (TG) showed significant (P<0.05) decrease after surgery, while high-density lipoprotein cholesterol (HDL-C) showed a significant increase during the first 3 months after surgery, in obese group. Total cholesterol and low-density lipoprotein cholesterol (LDL-C) decreased. However, the effect was significant for only a limited time period after surgery. Mean percentages of BW loss and TG decrease were greater in the obese group after surgery, however, the change was significant for only a limited time period after surgery. Mean percentage of HDL-C increase in non-obese group was greater but was not statistically significant. There were no differences in mean percentages of total cholesterol and LDL-C decrease between the two groups.
Conclusion: At 12 months after surgery, all groups showed significant improvement in BW and serum lipid profile. However, mean percentages in BW loss, TG decrease, and HDL-C increase between the two groups were different.
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KEYWORD
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Bariatric surgery, Roux-en-Y gastric bypass, Lipids
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